BCAA 5000
MVP's Pure 100% BCAA 5000 Powder provides a 5000 mg blend per serving of the three Branched Chain Amino Acids (L-Valine, L-Leucine and L-Isoleucine) in every serving. The Branched Chain Amino Acids (BCAA's), so named because of their unique branched chemical structure, are essential in that the body cannot make them from other compounds. In recent times, these amino acids have been investigated for their potential anticatabolic (preventing muscle breakdown) and anabolic (muscle building) effects.(1)

Other studies have shown that BCAA’s increase nitrogen retention, protein synthesis, and muscle tissue recuperation. They account for up to 90% of total amino acid uptake by the muscles.(2) The three BCAA’s are combined in balanced proportions to ensure maximum absorption into the body. Ideal for individuals who want maximum muscle tissue growth and repair.(3) *.

(1) Anthony JC, Anthony TG, Layman DK. Leucine supplementation enhances skeletal muscle recovery in rats following exercise. J Nutr. 1999 Jun;129(6):1102-6.
(2) De Palo EF, Gatti R, Cappellin E, Schiraldi C, De Palo CB, Spinella P. Plasma lactate, GH and GH-binding protein levels in exercise following BCAA supplementation in athletes. Amino Acids. 2001;20(1):1-11.
(3) Galassetti, P., Gibbons, F., Hamilton, K., Lacy, D., Cherrington, A., Wasserman, D. Enhanced muscle glucose uptake facilitates nitrogen efflux from exercised muscle. J Appl Physiol. June 1, 1998; 84(6): 1952 – 1959

What do they do? - Branched-chain amino acids (BCAAs) include leucine, isoleucine, and valine.  BCAAs are needed for the maintenance of muscle tissue; they also are needed during times of physical stress and intense exercise. Research shows that BCAA supplements helps those with amyotrophic lateral sclerosis (Lou Gehrig’s disease) maintain muscle strength. 1 In addition, individuals with liver disease (hepatic encephalopathy) benefit from intravenous administration of BCAAs. 2

Where are they found? - Dairy and red meat contain the greatest amount of BCAAs, although they are present in all protein—containing foods. Whey protein and egg protein supplements are other sources of BCAAs. BCAA supplements provide the single amino acids leucine, isoleucine, and valine.

In what conditions might BCAA's be supportive?
• athletic support
• post-surgery recovery

Who is likely to be deficient? - Periods of physical stress, such as intense weight lifting and long—distance running, can create a catabolic state in which muscle tissue is broken down. In these situations, supplemental BCAAs—particularly leucine and its derivatives ketoisocaproate (KIC) and hydroxymethylbutyrate (HMB)—can be beneficial in reducing protein breakdown. Nonetheless, BCAA supplements may reduce muscle loss and speed muscle gain. BCAAs may also be useful to anyone wanting to prevent muscle breakdown.

How much should I take? - A diet including animal protein provides an adequate amount of BCAA for most people. Athletes involved in intense training often take 5 grams of leucine, 4 grams of valine, and 2 grams of isoleucine per day to prevent muscle loss and increase muscle gain.

Are there any side effects or interactions? - Side effects have not been reported with the use of BCAAs. A high intake of BCAAs are simply converted into other amino acids or used as energy.

It is prudent to take BCAAs along with whole proteins, such as lean meat or poultry, and multiple vitamins/minerals, especially the B-complex vitamins.

References:

(1). Plaitakis A, Smith J, Mandeli J, et al. Pilot trial of branched-chain amino acids in amyotrophic lateral sclerosis. Lancet May 7, 1988:1015-8.
(2). Wahren J, Denis J, Desurmont P, et al. Is intravenous administration of branched chain amino acids effective in the treatment of hepatic encephalopathy? A multicenter study. Hepatology 1983;3(4):475-80.
(3). Kelly GS. Sports Nutrition: A review of selected nutritional supplements for bodybuilders and strength athletes. Med Rev 1997;2:184-201.
(4). MacLean DA, Graham TE, Satlin B. Branched-chain amino acids augment ammonia metabolism while attenuating protein breakdown during exercise. Am J Physiol 1994;267:E1010-1022.
(5). Blomstrand E, Hassmen P, Ek S, et al. Influence of ingesting a solution of branched-chain amino acids on perceived exertion during exercise. Acta Physiol Scand 1997;159:41-49.
(6). Van Hall G, Rasymakers JSH, Saris WHM, Wagenmakers AJM. Supplementation with branched-chain amino acids (BCAA) and tryptophan has no effect on performance during prolonged exercise. Clin Sci 1994;87:52 (abstract #75).

Suggested Use: Mix one rounded teaspoon into your favorite beverage, protein shake or meal replacement and consume 1-3 times daily or use as directed by a physician or licensed nutritionist..